产品说明
一般描述
Glial fibrillary acidic protein (GFAP) is an intermediate-filament protein found in the astrocytes of CNS (central nervous system).{56,59} It is located on chromosome 17q21.
The antibody detects endogenous level of total GFAP protein.
免疫原
Peptide sequence around aa. 423-427 (E-S-K-Q-E), according to the protein NP_002046.1
生化/生理作用
Glial fibrillary acidic protein (GFAP) regulates intermediate filament network dynamics, cell morphology and focal adhesions. It helps in maintaining myelination and stability of CNS (central nervous system) white matter architecture.
特点和优势
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目标描述
GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
外形
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
偶联物 | unconjugated |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
分子量 | ~50 kDa |
species reactivity | rat, human |
浓度 | 1 mg/mL |
technique(s) | western blot: 1:500-1:1000 |
同位素/亚型 | IgG |
免疫原序列 | (E-S-K-Q-E) |
NCBI登记号 | NM_002055.3 |
UniProt登记号 | P14136 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... GFAP(2670) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |