产品说明
一般描述
Galectins are a family of carbohydrate binding proteins. Galectin-7 was initially isolated from human keratinocytes as a novel member of S-lectin family that was responsive to retinoic acid but not detectable in epidermal tumors or squamous carcinomas. It is an early transcriptional target of the tumor suppressor P53 and inducible by UV radiation as well. Galectin-7 is also an enhancer of apoptosis, whereas galectin-1 induces tumorigenicity and resistance to apoptosis in several types of cancers. Recent research demonstrates that Galectin-7 acts as an adhesion molecule during implantation, and increased expression of Galectin-7 is associated with miscarriage, thus Galectin-7 is also being studied as a possible biomarker for miscarriage prediction.
免疫原
KLH-conjugated beta-galactose binding region corresponding to human Galectin-7.
应用
Research Category
Cell Structure
This Anti-Galectin-7 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of Galectin-7.
Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected Galectin-7 in human skin and human larynx tissue.
Research Sub Category
Adhesion (CAMs)
质量
Evaluated by Western Blotting in human skin tissue lysate.
Western Blotting Analysis: A 1:1,000 dilution of this antibody detected Galectin-7 in 10 µg of human skin tissue lysate.
目标描述
~16 kDa observed
外形
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Affinity purified
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
其他说明
Concentration: Please refer to lot specific datasheet.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
质量水平 | 300 |
生物来源 | rabbit |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
纯化方式 | affinity chromatography |
species reactivity | human |
species reactivity (predicted by homology) | chimpanzee (based on 100% sequence homology), baboon (based on 100% sequence homology), primate (based on 100% sequence homology), monkey (based on 100% sequence homology) |
technique(s) | immunohistochemistry: suitable western blot: suitable |
NCBI登记号 | NP_001035972 |
UniProt登记号 | P47929 |
运输 | wet ice |
安全信息
储存分类代码 | 10 - Combustible liquids |