产品说明
一般描述
Ferritin light (FTL) subunit along with ferritin heavy (FTH) subunit are members of the ferritin complex. FTL gene is mapped on the human chromosome at 19q13.33.
免疫原
Peptide with sequence C-GEYLFERLTLKHD from the C Terminus of the protein sequence according to NP_000137.2.
应用
Anti-FTL antibody produced in goat has been used in western blotting (1:500).
生化/生理作用
Ferritin light (FTL) subunit is an important protein in iron metabolism but lacks catalytic activity. This protein participates in the nucleation and mineralization of the iron center. FTL acts as a biomarker to differentiate between malignant and benign tumors. Overexpression of the FTL gene is observed in several malignant tumors and plays an important role in mediating the malignancy of cancers. FTL gene plays a role in the pathogenesis of glioblastoma. Mutation or deletion of the FTL gene is associated with neuroferritinopathy.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
产品性质
| 质量水平 | 100 |
| 生物来源 | goat |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| species reactivity | human, rat, mouse |
| technique(s) | indirect ELISA: suitable western blot: suitable |
| UniProt登记号 | P02792 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... FTL(2512) |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
