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Anti-Ezrin antibody, Mouse monoclonal

品牌
Sigma-Aldrich
货号
SAB4200806
规格纯度
clone 3C12, purified from hybridoma cell culture
参考价格
2130.37 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Ezrin, also known as cytovillin, p81 or 80K, is a.member of the ERM proteins family composed of Ezrin, Radixin, and Moesin. These proteins are known as actin-binding proteins that link the cell membrane to the actin cytoskeleton, particularly in microvillus-bearing epithelial cells. Ezrin is present in microvilli, microspikes, and membrane ruffles of cells.
The ERM proteins family are involved in the functional expression of membrane proteins on the cell surface, integrate Rho guanosine 5′-triphosphatase (GTPase) signaling regulating cytoskeletal organization and act as protein kinase A (PKA)-anchoring proteins. Therefore, ERM proteins seem to play an important role in the membrane transport of electrolytes by ion channels and transporters.

免疫原

The carboxy-terminal part of recombinant human ezrin

应用

Monoclonal Anti-Ezrin recognizes an epitope located on the C-terminal region of Ezrin. Reactivity has been observed with human, mouse, hamster, monkey, bovine, canine, rat and rat-kangaroo origin. The antibody is recommended to use in various immunological techniques, including Immunoblotting (~80kDa), immunofluorescence, Immunohistochemistry and immunoprecipitation.

外形

Supplied as a solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide as a preservative.

其他说明

This product is for R&D use only, not for drug, household, or other uses.

基本信息

NACRESNA.41

产品性质

生物来源mouse
抗体形式purified from hybridoma cell culture
antibody product typeprimary antibodies
克隆3C12, monoclonal
形式buffered aqueous solution
分子量 ~80 kDa
species reactivitymonkey, hamster, mouse, canine, human, rat, kangaroo, bovine
包装antibody small pack of 25 μL
浓度~1 mg/mL
technique(s)immunoblotting: 1-2 μg/mL using using canine MDCK cells extract
immunofluorescence: 0.5-1  μg/mL using human epidermoid carcinoma A431 cells.
同位素/亚型IgG1
UniProt登记号P15311
运输dry ice
储存温度−20℃

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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