产品说明
一般描述
Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the ′beads on a string′ structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.
特异性
Broad species reactivity is expected based on immunogen sequence similarities.
应用
This Anti-dimethyl Histone H3 (Arg26) antibody, Asymmetric is validated for use in western blotting, ICC & dot blot for the detection of dimethyl Histone H3 (Arg26).
Immunocytochemistry Analysis: A 1:500 dilution from a representative lot detected dimethyl Histone H3 (Arg26), Asymmetric in A431 and HepG2 cells.
Dot Blot (Specificity) Analysis: 0.5 µg/mL from a representative lot detected dimethyl Histone H3 (Arg26), Asymmetric in Absurance
DyLight
质量
Evaluated by Western Blotting in untreated and CARM1 treated HeLa acid extracts.
Western Blotting Analysis: 1 µg/mL of this antibody detects dimethyl Histone H3 (Arg26), Asymmetric in 10 µg of CARM1 treated HeLa acid extract.
目标描述
~17 kDa observed
外形
Affinity purified
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 纯化方式 | affinity chromatography |
| species reactivity | human |
| technique(s) | dot blot: suitable immunocytochemistry: suitable western blot: suitable |
| NCBI登记号 | NP_003520 |
| UniProt登记号 | P68431 |
| 运输 | wet ice |
| Gene Information | human ... HIST1H3F(8968) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
