产品说明
一般描述
Anti-DGKI Antibody detects endogenous levels of total DGKI protein.
DGKI (Diacylglycerol kinase iota) is a small, integral membrane protein belonging to the type IV diacylglycerol kinase subfamily. It is mapped on chromosome 7q32.3-q33. The members of the DGK family consist of a catalytic domain and at least two cysteine-rich regions. In type IV family members, it has four ankyrin repeats and a carboxy terminal PDZ binding domain.
免疫原
The antiserum was produced against synthesized peptide derived from human DGKI.
Immunogen Range: 991-1040
应用
Anti-DGKI, C-Terminal antibody produced in rabbit is suitable for indirect immunofluorescence and western blot.
生化/生理作用
DGKI (Diacylglycerol kinase iota) is mainly involved in the maintenance of intracellular concentration of diacylglycerol by phosphorylating other lipids in addition to DAG. DGKI has been predicted to be a potential gene for tumor suppression in colorectal cancers and mutation in DGKI has been linked to the melanoma.
特点和优势
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外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
基本信息
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
偶联物 | unconjugated |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
分子量 | antigen 116 kDa |
species reactivity | rat, human |
浓度 | ~1 mg/mL |
technique(s) | ELISA: 1:20000 immunofluorescence: 1:100-1:500 western blot: 1:500-1:1000 |
NCBI登记号 | O75912 |
UniProt登记号 | O75912 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... DGKI(9162) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | nwg |
闪点(F) | Not applicable |
闪点(C) | Not applicable |