产品说明
一般描述
Dermo-1, also known as Twist-related protein 2, is a basic helix-loop-helix transcription factor that has been shown to be a negative regulator for gene transcription and apoptosis. Basic helix-loop-helix transcription factors are implicated in cell lineage determination and differentiation. Dermo-1 shares extensive homology with another basic helix-loop-helix transcription factor, Twist. Studies suggest that Dermo-1 may inhibit osteoblast maturation during osteoblast development and maintain cells in preosteoblast phenotype.
免疫原
KLH-conjugated linear peptide corresponding to human Dermo-1.
应用
Research Sub Category
Transcription Factors
Research Category
Stem Cell Research
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Dermo-1 in rat liver tissue.
Anti-Dermo-1 Antibody is an antibody against Dermo-1 for use in WB, IH(P).
质量
Evaluated by Western Blot in rat liver tissue lysate.
Western Blot Analysis: 0.05 µg/mL of this antibody detected Dermo-1 on 10 µg of rat liver tissue lysate.
目标描述
~18 kDa observed
外形
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Affinity purified
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
分析说明
Control
Rat liver tissue lysate
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
纯化方式 | affinity chromatography |
species reactivity | human, rat |
species reactivity (predicted by homology) | mouse (based on 100% sequence homology), chicken (based on 100% sequence homology) |
technique(s) | immunohistochemistry: suitable (paraffin) western blot: suitable |
NCBI登记号 | NP_476527 |
UniProt登记号 | Q8WVJ9 |
运输 | wet ice |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |