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Anti-CYP3A4 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB5700096
包装型号
规格纯度
参考价格
4314.62 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified.

免疫原

Recombinant fusion protein containing a sequence corresponding to amino acids 244-503 of human CYP3A4 (NP_059488.2).

外形

PBS with 0.02% sodium azide,pH7.3.

储存及稳定性

Store at 4℃. Avoid freeze / thaw cycles.

产品性质

生物来源rabbit
质量水平100
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量 57
species reactivityhuman, rat, mouse
浓度0.77 mg/ml
technique(s)immunofluorescence: 1:20-1:100
immunohistochemistry: 1:20-1:50
western blot: 1:500-1:1000
UniProt登记号P08684
运输wet ice
储存温度2-8℃
Gene Informationhuman ... CYP3A4(1576)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

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