产品说明
一般描述
Conserved oligomeric Golgi (COG) complex 2 is also known as LDLC. COG complex is a multi-subunit protein complex, composed of eight distinct subunits. This protein is highly conserved with two heterotrimeric groups, Cog2-Cog3- Cog4 and Cog5-Cog6-Cog7 in its structure.
免疫原
synthetic peptide corresponding to the C-terminal region of human COG2, conjugated to KLH. The corresponding sequence is identical in monkey and bovine and differs by four amino acids in rat and mouse COG2.
应用
Anti-COG2 antibody produced in rabbit has been used in:
- immunoblotting
- immunoprecipitation
- immunofluorescence
生化/生理作用
Conserved oligomeric Golgi (COG) complex 2 regulates membrane trafficking and maintenance of Golgi glycosylation machinery in eukaryotic cells. COG2 is needed for normal Golgi morphology and function. COG2 interacts with p115 (golgin), a vesicle tethering protein that functions in endoplasmic reticulum-Golgi trafficking. This interaction is required for Golgi integrity.
外形
Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 偶联物 | unconjugated |
| 抗体形式 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen ~83 kDa |
| species reactivity | human |
| technique(s) | immunoblotting: 1:1000-1:2000 using whole extracts of hamster CHO cells. immunoprecipitation (IP): 2.5-5.0 μL using lysates of human HeLa cells indirect immunofluorescence: 1:2,500-1:5,000 using human HeLa cells. |
| UniProt登记号 | Q14746 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... COG2(22796) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
