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Anti-Claudin-4 (C-terminal) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4200574
规格纯度
affinity isolated antibody
参考价格
4618.16 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Claudin-4 is heterogeneously expressed in various tissues. It is enriched in endothelial cells (ECs), including the blood-brain barrier, and is also expressed in gut and kidney. It is mapped to human chromosome 7q11.23. Claudin-4 is associated with the tight junction strands in kidney epithelial cells.

特异性

Anti-Claudin-4 (C-terminal) specifically recognizes human, rat and dog claudin-4.

应用

Anti-Claudin-4 (C-terminal) antibody produced in rabbit has been used in:

  • immunoblotting
  • immunofluorescence
  • immunohistochemistry

生化/生理作用

Claudin-4 is involved in maintaining cellular polarity. It favors sodium chloride absorption and acts as a cation-barrier. Claudin-4 expression has been shown to be deregulated in several cancers, with aberrant expression in ovarian, breast, prostate and pancreatic carcinomas. The gene location of claudin-4 is a Williams-Beuren syndrome critical region.

外形

Supplied as a solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

储存及稳定性

For continuous use, store at 2-8 ℃ for up to one month. For extended storage, freeze in working aliquots. Repeated freezing and thawing, or storage in “frost-free” freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilutions should be discarded if not used within 12 hours.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
species reactivityrat, human, canine
technique(s)immunoblotting: suitable
immunofluorescence: suitable
immunohistochemistry: suitable
UniProt登记号P01275
储存温度−20℃
Gene Informationhuman ... CLDN4(1364)

安全信息

储存分类代码12 - Non Combustible Liquids
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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