产品说明
特异性
Reacts with a wide range of cartilage proteoglycans after either chondroitinase (ABC or AC) or testicular hyaluronidase digestion. Native proteoglycans do not react with MAB2035. Antibody binding to epitope is successfully inhibited by disaccharides of chondroitin-6-sulfate. Recognizes the chondroitin-6-sulfate stubs (preferentially in clusters) of high density cartilage proteoglycans of different species. No cross-reactivity with dermatan sulfate, keratan sulfate or chondroitin-4-sulfate.
免疫原
Chondroitinase ABC-digested adult human aggrecan.
应用
ELISA at 1:100-1:5,000
RIA at 1:100-1:200.
Chondroitinase ABC digestion prior to antibody reaction is required for antibody reactivity. {0.5U/mL in 100mM Tris-HCL, 30 minutes room temperature} A dramatic proteolytic digestion of the core protein (e.g. with papain or pronase) significantly reduces the antibody reactivity.
Optimal working dilutions must be determined by the end user.
Anti-Chondroitin 6 Sulfate Antibody, clone MK-302 is an antibody against Chondroitin 6 Sulfate for use in ELISA, RIA & WB.
外形
Ascites liquid; no preservative.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
产品性质
| 质量水平 | 100 |
| 生物来源 | mouse |
| 抗体形式 | ascites fluid |
| antibody product type | primary antibodies |
| 克隆 | MK-302, monoclonal |
| species reactivity | human, mouse, sheep, bovine, canine, rat, rabbit |
| manufacturer/tradename | Chemicon® |
| technique(s) | ELISA: suitable radioimmunoassay: suitable western blot: suitable |
| 同位素/亚型 | IgG1 |
| NCBI登记号 | NM_001135.2 NM_013227.2 |
| UniProt登记号 | P16112 |
| 运输 | dry ice |
| Gene Information | human ... ACAN(176) |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
