产品说明
一般描述
Acetylcholine (ACh) is a common neurotransmitter for motoneurons, preganglionic autonomic neurons, postganglionic parasympathetic neurons, a variety of brain regions and some emerging neuron-like stem cells. The metabolism of Ach is relatively simple, involving only two enzymes: choline acetyltransferase (ChAT) for synthesis and acetylcholinesterase (AChE) for degradation. Further, acetylcholine has little function in neurons other than neurotransmission and seems to be neuron specific. It seems that only cholinergic neurons have significant amounts of ChAT making anti-cholinacetyltransferase a useful specific marker.
特异性
Recognizes cholinergic neurons in brain and central nervous systems.
免疫原
Human placental enzyme.
应用
Immunoblot: 1:1,000-1:5,000
Immunohistochemistry: 1:500-1:1,000. See page two of this data sheet.
Optimal working dilutions must be determined by the end user.
Research Sub Category
Neurotransmitters & Receptors
Neuronal & Glial Markers
Research Category
Neuroscience
Anti-Choline Acetyltransferase Antibody is an antibody against Choline Acetyltransferase for use in IH & WB.
目标描述
70 kDa
外形
Unpurified
Goat antisera, liquid, no preservatives.
储存及稳定性
Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
分析说明
Control
Rat brain tissue
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
产品性质
| 质量水平 | 100 |
| 生物来源 | goat |
| 抗体形式 | serum |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| species reactivity | rat, guinea pig, mouse |
| manufacturer/tradename | Chemicon® |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI登记号 | NM_020549.3 NM_020984.2 NM_020985.2 NM_020986.2 |
| UniProt登记号 | P28329 |
| 运输 | dry ice |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
