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Anti-Cellular Fibronectin antibody, Mouse monoclonal

品牌
Sigma-Aldrich
货号
SAB4200784
规格纯度
clone FN-3E2, hybridoma cell culture supernatant
参考价格
6010.98 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Anti-Cellular Fibronectin antibody, Mouse monoclonal (mouse IgM isotype) is derived from the FN-3E2 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from mice immunized with the antigens released in culture from a breast cancer cell line. Fibronectin (FN), also known as cold-insoluble globulin (CIG), is an extracellular matrix multi-domain glycoprotein composed of two nearly identical disulphide bound polypeptides. Fibronectin 1 is a glycoprotein, that is coded by FN1 gene. It is expressed in the plasma and at the cell surface. It is mapped to human chromosome 2q35. Cellular fibronectin is produced by various cell types, including fibroblasts, endothelial cells, chondrocytes, synovial cells, and myocytes.

免疫原

Antigens released in culture from a breast cancer cell line

应用

Anti-cellular Fibronectin antibody, mouse monocloneal has been used in various immunochemical techniques including immunoblotting (220-260 kDa), immunofluorescence, and immunohistochemistry.
Anti-Cellular Fibronectin antibody, Mouse monoclonal has been used in:

  • immunoblotting
  • immunofluorescence
  • immunohistochemistry

生化/生理作用

Fibronectin participates in cell adhesion, growth, migration, wound healing, blood coagulation and metastasis. Mutations in FN1 results in glomerulopathy. It plays an important role in cell attachment and spreading, control of cell cytoskeleton, morphology and differentiation. FN1 is also involved in extracellular matrix formation, haemostasis and thrombosis. It is a ubiquitous and essential component of the extracellular matrix (ECM) and plays a vital role in tissue repair mechanism.

外形

The product is supplied as a culture supernatant solution containing 15 mM sodium azide as a preservative. The product contains fetal calf serum.

其他说明

This product is for R&D use only, not for drug, household, or other uses.

基本信息

NACRESNA.41

产品性质

质量水平200
生物来源mouse
抗体形式culture supernatant
antibody product typeprimary antibodies
克隆FN-3E2, monoclonal
形式buffered aqueous solution
分子量 ~220-260 kDa
species reactivityrat, human, mouse, chicken
technique(s)immunoblotting: suitable
immunofluorescence: 1:2,000-1:4,000 using human foreskin fibroblast Hs68 cells
immunohistochemistry: suitable
同位素/亚型IgM
UniProt登记号 P02751
运输dry ice
储存温度−20℃

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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