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Anti-CD10 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4300659
规格纯度
affinity isolated antibody
参考价格
5045.46 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Cluster of differentiation 10 (CD10) is also known as neprilysin (NEP), that is encoded by MME (membrane metallo-endopeptidase) gene. It has 24 exons and is located on chromosome 3q25.1 to q25.2. It is predominantly expressed in kidney. The protein is made of 742 amino acids with molecular weight of nearly 85 to 110kDa.

The antibody detects endogenous level of total CD10 protein.

免疫原

Peptide sequence around aa. 6-10 (S-Q-M-D-I), according to the protein NP_000893.2

生化/生理作用

Cluster of differentiation 10 (CD10) plays an important role in the degeneration of neuropeptides. It participates in several renal diseases. It plays a major role in Alzheimer′s disease. It helps in the degradation of β‐amyloid (Aβ) in the central nervous system (CNS).

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

目标描述

Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers.

外形

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量 ~100 kDa
species reactivityhuman, mouse, rat
浓度1 mg/mL
technique(s)western blot: 1:500-1:1000
同位素/亚型IgG
免疫原序列(S-Q-M-D-I)
NCBI登记号NM_000902.3
运输wet ice
储存温度−20℃
Gene Informationhuman ... CD10(4311)

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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