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Anti-CD86 (B7-2) Antibody (mouse), PE, clone GL-1

品牌
Sigma-Aldrich
货号
MABF458
规格纯度
clone GL-1 (GL1), 0.2 mg/mL, from rat
参考价格
3841.74 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

The GL-1 antibody reacts with mouse CD86, also known as B7-2, an 80 kDa cell surface protein which is a ligand for CD28, a co-stimulatory receptor for the T cell receptor (TCR). CD28 can also bind a second B7 ligand known as CD80 (B7-1). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response. The GL-1 antibody may be used as a marker for CD86 expression on B cells, macrophages, and dendritic cells.

免疫原

Immunogen information for this antibody is proprietary information.

应用

This rat monoclonal antibody Anti-CD86 (B7-2) (mouse), PE, clone GL-1 validated for use in IHC, Immunofluorescence & Flow Cytometry for the detection of CD86 (B7-2).
Research Category
Inflammation & Immunology

质量

The monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

Flow Cytometry Analysis: 0.125 µg of this antibody detected CD86 (B7-2) in one million C57Bl/6 splenocytes.

外形

Size Exclusion Chromatography
Purified Rat Monoclonal Antibody in buffer containing 10 mM NaH2PO4, 150 mM NaCl, 0.1% gelatin, pH 7.2, and up to 0.1% sodium azide.

储存及稳定性

It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

质量水平100
生物来源rat
偶联物PE
抗体形式purified antibody
antibody product typeprimary antibodies
克隆GL-1 (GL1), monoclonal
species reactivitymouse
浓度0.2 mg/mL
technique(s)flow cytometry: suitable
immunofluorescence: suitable
immunohistochemistry: suitable
同位素/亚型IgG2aκ
UniProt登记号P42082
运输wet ice

安全信息

储存分类代码12 - Non Combustible Liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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