产品说明
一般描述
C-C motif chemokine receptor 5 (CCR5) is expressed by T lymphocytes, macrophages and monocytes. It belongs to the chemokine receptor family. The gene encoding this protein is localized on human chromosome 3p21.31.
免疫原
a peptide corresponding to amino acids 6-20 of human CCR5.
生化/生理作用
C-C motif chemokine receptor 5 (CCR5) is a receptor for chemokine ligands-3, -4 and -5. It acts as a co-receptor for human immunodeficiency virus (HIV) entry in cells.The protein also has a role in leukocyte chemotaxis. CCR5 indirectly influence the aggregation of immune cells at the site of viral infection on mucosal surfaces. It also modulates activation of immune cells during inflammation.
联系
The action of this antibody can be blocked using blocking peptide SBP1112.
外形
Solution in phosphate buffered saline containing 0.02% sodium azide
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
MDL编号 | MFCD01864608 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
偶联物 | unconjugated |
抗体形式 | IgG fraction of antiserum |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
分子量 | predicted mol wt 39 kDa |
species reactivity | human |
technique(s) | immunohistochemistry: suitable indirect ELISA: suitable western blot: suitable |
UniProt登记号 | P51681 |
运输 | dry ice |
储存温度 | −20℃ |
Gene Information | human ... CCR5(1234) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |