产品说明
一般描述
Caspase 12 (CASP12), a member of the caspase family, is expressed in the Golgi complex.
免疫原
a peptide corresponding to amino acids 2-17 of murine caspase-12.
应用
Anti-CASPASE-12 (ab1) antibody produced in rabbit has been used in western blotting.
生化/生理作用
Murine caspase 12 (CASP12) is activated during endoplasmic reticulum stress and activates other caspases which act on substrates, ultimately leading to apoptosis. The protein has been shown to be activated during progression of retinal degeneration in animal models. In mice models, CASP12 has been shown to cause neuronal death resulting from ischemia/reperfusion.
联系
The action of this antibody can be blocked using blocking peptide SBP2325.
外形
Solution in phosphate buffered saline containing 0.02% sodium azide
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| MDL编号 | MFCD03454856 |
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | predicted mol wt 46 kDa |
| species reactivity | rat, mouse, human |
| technique(s) | immunohistochemistry: suitable indirect ELISA: suitable western blot: suitable |
| UniProt登记号 | O08736 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | mouse ... Casp12(12364) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
