产品说明
特异性
CASK. The immunogen protein represents a CASK-specific domain that lies between the calmodulin binding and PDZ domains. MAB5230 exhibits a specific reaction to the two alternatively spliced isoforms of CASK present in the mammalian CNS, the CASK-B or long (~900 amino acid) isoform present in rat brain membrane preparations, and the soluble CASK-A or short (~600 amino acid) isoform.CASK is a synapse-associated Ca2+/calmodulin-dependent protein kinase that also contains PDZ, SH3 and guanylate kinase domains. CASK is thought to play a critical role in synaptic vesicle exocytosis and synaptic junctions.
免疫原
CASK-GST fusion protein (amino acids 318-415).
应用
Anti-CASK Antibody, clone K56A is an antibody against CASK for use in WB, IC, IH.
Research Category
Neuroscience
Research Sub Category
Synapse & Synaptic Biology
Western blot: 1 μg/mL
Immunocytochemistry: 0.5-1.0 μg/mL
Immunohistochemistry on 4% paraformaldehyde fixed tissue: 0.5- 1.0 μg/mL
Optimal working dilutions must be determined by the end user.
外形
Purified immunoglobulin. Liquid in 0.02M Phosphate buffer, 0.25M NaCl with 0.1% sodium azide.
Format: Purified
储存及稳定性
Maintain at 2-8°C in undiluted aliquots up to 6 months.
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| eCl@ss | 32160702 |
产品性质
| 质量水平 | 100 |
| 生物来源 | mouse |
| 抗体形式 | purified immunoglobulin |
| antibody product type | primary antibodies |
| 克隆 | K56A, monoclonal |
| species reactivity | rat, mouse, human |
| manufacturer/tradename | Chemicon® |
| technique(s) | immunocytochemistry: suitable immunohistochemistry: suitable western blot: suitable |
| 同位素/亚型 | IgG1 |
| NCBI登记号 | NM_003688.1 |
| UniProt登记号 | O14936 |
| 运输 | wet ice |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
