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Anti-Bst2 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB3501233
规格纯度
affinity isolated antibody
参考价格
4802.96 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Bst2 Antibody: Bst2 was first identified as a novel terminal B-cell-restricted antigen termed HM1.24 that is expressed on certain bone marrow cells as well as other tissues. The surface expression of Bst2 on fibroblast cell lines facilitated the stromal cell-dependent growth of DW34, a pre-B-cell line, suggesting that this protein is involved in pre-B-cell growth. Later experiments also showed it to be upregulated in several myeloma cells. More recently, Bst2 was identified an inhibitor of retroviral release from human cells whose activity is antagonized by the HIV-1 accessory protein Vpu. While Bst2 caused retention of virions on cell surfaces or endocytosis into Bst2-positive compartments, its depletion abolished the viral requirement for Vpu for virus release. This activity may represent a potential therapeutic strategy for the treatment of HIV/AIDS.

免疫原

Bst2 antibody was raised against a 18 amino acid synthetic peptide near the amino terminus of the mouse Bst2.The immunogen is located within amino acids 60 - 110 of Bst2.

应用

Bst2 antibody can be used for detection of Bst2 by Western blot at 1 - 2 μg/mL. Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

外形

Supplied in PBS containing 0.02% sodium azide.

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式liquid
species reactivityhuman, mouse
浓度1 mg/mL
technique(s)western blot: suitable
同位素/亚型IgG
UniProt登记号Q8R2Q8
运输wet ice
储存温度−20℃
Gene Informationmouse ... Bst2(69550)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable

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