Anti-β-Amyloid (1-42) Rabbit pAb

产品说明

一般描述

Rabbit polyclonal antibody adsorbed against Aβ_1-40 and Aβ_1-43, followed by immunoaffinity purification. Recognizes specifically β-amyloid peptide (1-42).
Recognizes specifically β-amyloid peptide (1-42). Does not cross-react with β-amyloid peptide (1-40) or β-amyloid peptide (1-43).

Antibody Target Gene Symbol: APP

Target Synonym: AAA, AD1, Adap, AL024401, Amyloid precursor, Amyloidogenic glycoprotein, APP isoform 1, APPI, appican, CTFgamma, CVAP, E030013M08RIK, Nexin II, P3, PN2, PreA4, PROTEASE NEXIN2

Entrez Gene Name: amyloid beta (A4) precursor protein

Hu Entrez ID: 351 (Related Antibodies: 171610, PC729,PC152, PC151, PC149, NE1012,171609, 171608, 171607, 171606, 171605, 171604, 171603, 171598, 171537)

Mu Entrez ID: 11820

Rat Entrez ID: 54226

This Anti-β-Amyloid (1-42) Rabbit pAb is validated for use in Dot Blot, ELISA, Radioimmunoassay for the detection of β-Amyloid (1-42).

免疫原

Human
a synthetic peptide corresponding to amino acids from a C-terminal fragment of human β-amyloid peptide (1-42)

包装

25 μg in Plastic ampoule
Please refer to vial label for lot-specific concentration.

应用

Dot Blot (0.1-0.5 µg/ml)

ELISA (0.1-0.5 µg/ml)

Radioimmunoassay (0.5 µg/ml)

警告

Toxicity: Standard Handling (A)

外形

In phosphate buffer, pH 7.4.

重悬

Following initial thaw, aliquot and freeze (-20°C).

其他说明

Savage, M.J., et al. 1998. J. Neurosci.15, 1743.
Borchelt, D.R., et al. 1997. Neuron19, 939.
Citron, M., et al. 1997. Nature Med.3, 67.
Hardy, J. 1997. Trends in Neurosci.20, 154.
Solomon, B., et al. 1997. Proc. Natl. Acad. Sci. USA94, 4109.
Duff, K., et al. 1996. Nature383, 710.
Iwatsubo, T., et al. 1994. Neuron13, 45.
Suzuki, N., et al. 1994. Science264, 133.
This antibody is specific for β-amyloid peptide [1-42] and shows no reactivity to β-amyloid peptide [1-40] or β-amyloid peptide [1-43]. This antibody is recommended for use in the quantitative determination of β-amyloid peptide [1-42]. The sensitivity level for sandwich ELISA is 15-25 pg. Antibody should be titrated for optimal results in individual systems.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

产品性质

生物来源	rabbit
质量水平	100
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
形式	liquid
不包含	preservative
species reactivity	human
包装	antibody small pack of 25 μg
manufacturer/tradename	Calbiochem®
储存条件	OK to freeze avoid repeated freeze/thaw cycles
同位素/亚型	IgG
运输	wet ice
储存温度	−20℃

安全信息

储存分类代码	10 - Combustible liquids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable