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Anti-ANGPT2 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB2109155
规格纯度
affinity isolated antibody
参考价格
5258.35 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Angpt2 binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. It can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.

免疫原

Synthetic peptide directed towards the middle region of Mouse Angpt2

序列

Synthetic peptide located within the following region: NQTTRLELQLLQHSISTNKLEKQILDQTSEINKLQNKNSFLEQKVLDMEG

外形

Supplied at 0.5 mg/ml in phosphate-buffered saline, 0.09% sodium azide

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

产品性质

生物来源rabbit
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量 56 kDa
species reactivity (predicted by homology)horse, pig, rabbit, bovine, canine, guinea pig, sheep, human, mouse
浓度0.5 mg/mL
technique(s)western blot: 1 μg/mL
NCBI登记号NM_007426
运输wet ice
储存温度−20℃
Gene Informationhuman ... ANGPT2(285)

安全信息

储存分类代码10 - Combustible liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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