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Anti-AIF antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB5701260
包装型号
规格纯度
参考价格
4668.88 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6 (COXPD6), a severe mitochondrial encephalomyopathy, as well as Cowchock syndrome, also known as X-linked recessive Charcot-Marie-Tooth disease-4 (CMTX-4), a disorder resulting in neuropathy, and axonal and motor-sensory defects with deafness and mental retardation. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10. [provided by RefSeq, Aug 2015]

免疫原

A synthesized peptide derived from human AIF.

外形

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

产品性质

生物来源rabbit
质量水平100
antibody product typeprimary antibodies
克隆monoclonal
形式liquid
species reactivityhuman, mouse, rat
浓度0.17 mg/mL
technique(s)immunohistochemistry: 1:50-1:200
western blot: 1:500-1:2000
UniProt登记号O95831
运输wet ice
储存温度−20℃
Gene Informationhuman ... AIFM1(9131)

安全信息

闪点(F)Not applicable
闪点(C)Not applicable

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