产品说明
一般描述
Monoclonal Anti-Actin (α-Sarcomeric) (mouse IgM isotype) is derived from the hybridoma 5C5 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with purified rabbit striated muscle. Actin is one of the major cytoskeletal proteins in eukaryotic cells.
免疫原
purified rabbit striated muscle
应用
Monoclonal Anti-Actin (α-Sarcomeric) antibody produced in mouse has been used in:
- western blotting
- enzyme linked immunosorbent assay (ELISA)
- immunohistochemistry
生化/生理作用
Actin plays an essential role in various cellular processes including cell migration, cytokinesis, vesicle transport, and contractile force generation. Pathological conditions influenced by genetic and/or environmental factors causes variations in the sarcomeric actin filaments. These variations in the actin filaments leads to the development of congenital myopathy, a genetic muscle disorder.
外形
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | mouse |
| 抗体形式 | purified from hybridoma cell culture |
| antibody product type | primary antibodies |
| 克隆 | 5C5, monoclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen ~42 kDa |
| species reactivity | human, carp, rabbit, frog, rat, bovine, snake, sheep, guinea pig |
| 浓度 | ~1.0 mg/mL |
| technique(s) | immunoblotting: suitable immunohistochemistry: 1-2 μg/mL using formalin-fixed, paraffin embedded human tongue indirect ELISA: suitable |
| 同位素/亚型 | IgM |
| 运输 | dry ice |
| 储存温度 | −20℃ |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
