位置:首页 > 品牌 > Sigma-Aldrich >

Anti-acetyl Histone H3 (Lys9), Alexa Fluor® 488 Conjugate Antibody

品牌
Sigma-Aldrich
货号
ABE18-AF488
规格纯度
from rabbit, ALEXA FLUOR® 488
参考价格
6861.94 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the ′beads on a string′ structure. Histone proteins are highly post-translationally modified however Histone H3 is the most extensively modified of the five histones. Histone H3 sequence variants and variable modification states are thought to play a role in the dynamic and long term regulation of genes. Trimethylation of histone H3 on Lys9 (H3K9me3) is one of the most highly studied epigenetic marks. H3K9me3 functions in the repression of euchromatic genes, and in epigenetic control of heterochromatin assembly, most likely by acting as a recognition motif for the binding of chromatin-associated proteins, such as Swi6 or HP1α. The enzymes responsible for H3K9 trimethylation are SUV39H1 and SUV39H2.

免疫原

Linear peptide corresponding to acetyl Histone H3 (Lys9).

应用

This Anti-acetyl Histone H3 (Lys9) is validated for use in Immunocytochemistry for the detection of acetyl Histone H3 (Lys9).
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Nuclear Receptors

质量

Evaluated by Immunocytochemistry in A431 cells.

Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected acetyl Histone H3 (Lys9) in A431 cells. ABE18-AF488 is derived from its parent antibody ABE18.
Alexa Fluor® is a registered trademark of Life Technologies.

目标描述

17 kDa observed. Molecular weight was observed with parent ABE18.

外形

Purified rabbit IgG in PBS containing 15 mg/mL BSA and 0.1% Sodium Azide.
Affinity purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

其他说明

Concentration: Please refer to lot specific datasheet.

法律信息

ALEXA FLUOR is a registered trademark of Life Technologies

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

生物来源rabbit
质量水平100
偶联物ALEXA FLUOR® 488
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
species reactivityhuman
species reactivity (predicted by homology)chicken (based on 100% sequence homology), mouse (based on 100% sequence homology)
technique(s)immunocytochemistry: suitable
NCBI登记号NP_003484
UniProt登记号Q16695
运输wet ice

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

推荐产品
| 首页 | 联系我们 | 会员服务 | 广告服务 | 友情链接 |
版权所有 CopyRight © 2008-2024 粤ICP备08119708号