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Anti-CTCF antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB5700957
包装型号
规格纯度
参考价格
3139.45 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms′ tumors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

免疫原

Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human CTCF (NP_006556.1).

外形

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

产品性质

生物来源rabbit
质量水平100
antibody product typeprimary antibodies
克隆polyclonal
形式liquid
species reactivityrat, human, mouse, monkey
浓度3.11 mg/mL
technique(s)immunohistochemistry: 1:50-1:200
western blot: 1:500-1:2000
UniProt登记号P49711
运输wet ice
储存温度−20℃
Gene Informationhuman ... CTCF(10664)

安全信息

闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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