产品说明
一般描述
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms.
免疫原
Recombinant protein of human CASP1.
外形
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | liquid |
| species reactivity | all |
| 浓度 | 2.3 mg/mL |
| technique(s) | western blot: 1:500-1:2000 |
| UniProt登记号 | P29466 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... CASP1(834) |
安全信息
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
