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AHCYActivity Fluorometric Assay Kit

AHCY 活性荧光检测试剂盒

品牌
Sigma-Aldrich
货号
EPI021
规格纯度
sufficient for 100 fluorometric tests
参考价格
11068.1 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Adenosylhomocysteinase (AHCY) (EC 3.3.1.1) or S-adenosylhomocysteine hydrolase (SAHH); is an enzyme that catalyzes the reversible hydrolysis of S-adenosyl homocysteine (SAH) to adenosine and homocysteine. AHCY regulates the intracellular SAH concentration which in turn regulates S-adenosyl methionine (SAM)-dependent methyltransferases. Down-regulation of AHCY has been associated with certain forms of cancer and Huntington′s disease, while in Wilson′s disease; the enzyme is inhibited by the accumulated copper. Mutations in the AHCY gene cause SAHH deficiency disease.

适用性

Suitable for the detection of Adenosylhomocysteinase (AHCY) activty in purified recombinant protein or cell and tissue lysate.

原理

The AHCY Activity Assay kit can kinetically measure AHCY activity by detecting adenosine generation resulting from the hydrolysis of SAH. Adenosine is detected via a multi-step reaction, resulting in the generation of an intermediate that reacts with the probe. The fluorescent product is measured at. limit of quantification (LOQ) is 1 U of recombinant human AHCY.

基本信息

NACRESNA.84

产品性质

detection methodfluorometric
储存温度−20℃

安全信息

象形图GHS05GHS07GHS08GHS09
警示用语:Danger
危险声明H312 - H317 - H318 - H334 - H361d - H410
预防措施声明P202 - P273 - P280 - P302 + P352 + P312 - P305 + P351 + P338 - P308 + P313
危险分类Acute Tox. 4 Dermal - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Repr. 2 - Resp. Sens. 1 - Skin Sens. 1
储存分类代码10 - Combustible liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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