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8-Aminoguanosine

品牌
Sigma-Aldrich
CAS
3868-32-4
货号
SML1852
包装型号
规格纯度
≥98% (HPLC)
参考价格
865.81 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

包装

25 mg in glass bottle

生化/生理作用

8-Aminoguanosine, a guanosine derivative, is an orally available and highly efficacious potassium-sparing diuretic/natriuretic that increased sodium excretion by 26.2-fold and decrease potassium excretion by 69.1%. 8-Aminoguanosine increases glucose excretion by 12.2-fold. Also 8-Aminoguanosine suppressed deoxycorticosterone/salt-induced hypertension.
8-Aminoguanosine is known to stimulate diuresis, natriuresis, glucosuria and antikaliuresis. It is an analog of guanosine, that can block purine nucleoside phosphorylase, in vitro and in intact lymphoid cells. 8-aminoguanosine triphosphate can be used to block GTP (guanosine triphosphate) cyclohydrolase I from human liver and Escherichia coli.

基本信息

经验(实验)分子式C10H14N6O5
分子量298.26

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 white to brown
溶解性DMSO: 1 mg/mL, clear (warmed)
储存温度2-8℃
SMILES stringNC1=NC(C2=C(N1)N([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C(N)=N2)=O
InChI1S/C10H14N6O5/c11-9-14-6-3(7(20)15-9)13-10(12)16(6)8-5(19)4(18)2(1-17)21-8/h2,4-5,8,17-19H,1H2,(H2,12,13)(H3,11,14,15,20)
InChI keyFNXPTCITVCRFRK-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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