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TRAIL from mouse

品牌
Sigma-Aldrich
货号
SRP3237
规格纯度
recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture
参考价格
4582.93 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a cytotoxic protein. Recombinant murine TRAIL is a 174 amino acid polypeptide (20.0kDa), consisting of the TNF homologous portion of the extracellular domain of the full length TRAIL protein.

生化/生理作用

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) activates rapid apoptosis in tumor cells, but not in normal cells. TRAIL-induced apoptosis is achieved through binding to two death-signaling receptors, death receptor 4 and 5 (DR4 and 5). These receptors belong to the tumor necrosis factor receptor (TNFR) superfamily of transmembrane proteins and contain a cytoplasmic "death domain", which activates the cell′s apoptotic machinery.

序列

MRGGRPQKVA AHITGITRRS NSALIPISKD GKTLGQKIES WESSRKGHSF LNHVLFRNGE LVIEQEGLYY IYSQTYFRFQ EAEDASKMVS KDKVRTKQLV QYIYKYTSYP DPIVLMKSAR NSCWSRDAEY GLYSIYQGGL FELKKNDRIF VSVTNEHLMD LDQEASFFGA FLIN

外形

Lyophilized from 10 mM Sodium Phosphate, pH 7.0.

重悬

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.5-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8℃ for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20℃ to -80℃.

基本信息

NACRESNA.32

产品性质

生物来源mouse
重组expressed in E. coli
测定≥95% (HPLC)
≥95% (SDS-PAGE)
形式lyophilized
效能40.0-60.0 ng/mL ED50
分子量 20.0 kDa
包装pkg of 50 μg
technique(s)cell culture | mammalian: suitable
杂质<0.1 EU/μg endotoxin, tested
颜色 white
UniProt登记号P50592
运输wet ice
储存温度−20℃
Gene Informationmouse ... TNFSF10(22035)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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