产品说明
一般描述
It binds and signals through the IL-1RL1/ST2 receptor activating NF-kappaB and MAP kinases. IL-33 induces production of TH2 cell related cytokines, including IL-4, IL-5 and IL-13, and exerts multiple inflammation related bioactivities.
生化/生理作用
Human IL-33 is a proinflammatory protein that shares structural and functional characteristics with the IL-1 cytokine family. Recombinant human IL-33 is a 17.9 kDa protein containing 159 amino acid residues.
外形
Lyophilized from 10 mM Sodium Phosphate, pH 8.0 + 0.5 mM DTT.
重悬
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2-8℃ for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20℃ to -80℃.
基本信息
NACRES | NA.32 |
产品性质
生物来源 | human |
重组 | expressed in E. coli |
测定 | ≥98% (HPLC) ≥98% (SDS-PAGE) |
形式 | lyophilized |
效能 | ≥0.05 ng/mL ED50 |
分子量 | 17.9 kDa |
包装 | pkg of 10 μg |
杂质 | <0.1 EU/μg endotoxin, tested |
颜色 | white to off-white |
UniProt登记号 | O95760 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... IL33(90865) |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |