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IL-17 human

品牌
Sigma-Aldrich
货号
SRP3080
规格纯度
Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture
参考价格
5283.88 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

The gene IL17A (interleukin 17A), also referred to as IL-17, is mapped to human chromosome 6p12.2. The gene contain three exons and encodes a proinflammatory cytokine produced by activated T cells.

生化/生理作用

The cytokine interleukin 17A is involved in the activation of proinflammatory cytokines, chemokines, and cell adhesion molecules in several cell types such as, macrophages, dendritic cells, T cells, synovial cells, and endothelial cells. Overexpression of this protein has been associated with rheumatoid arthritis, systemic lupus erythematosus, Behcet′s disease, allograft rejection, nephritic syndrome, asthma, and multiple sclerosis. In mice, it has been observed to be implicated in the development of allergic and autoimmune diseases. Polymorphism in IL17A gene has been associated with lung cancer.

序列

MIVKAGITIP RNPGCPNSED KNFPRTVMVN LNIHNRNTNT NPKRSSDYYN RSTSPWNLHR NEDPERYPSV IWEAKCRHLG CINADGNVDY HMNSVPIQQE ILVLRREPPH CPNSFRLEKI LVSVGCTCVT PIVHHVA

外形

Lyophilized with no additives.

重悬

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8℃ for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a stabilizer (example 5% Trehalose) and store in working aliquots at -20℃ to -80℃.

基本信息

NACRESNA.32

产品性质

生物来源human
重组expressed in E. coli
测定≥98% (HPLC)
≥98% (SDS-PAGE)
形式lyophilized
分子量 31.0 kDa
包装pkg of 25 μg
technique(s)cell culture | mammalian: suitable
杂质<0.1 EU/μg endotoxin, tested
颜色 off-white to yellow
UniProt登记号Q16552
运输wet ice
储存温度−20℃
Gene Informationhuman ... IL17A(3605)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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