CD40 Ligand/TRAP Protein, Recombinant human

产品说明

一般描述

Product Source: Recombinant human
CD40 Ligand (CD40L/TRAP) is a type II membrane protein which, effectuates the helper function of T cells on resting B cells. GF101 is a 16.3 kDa protein containing 149 amino acid residues comprising the receptor binding TNF-like domain of CD40L.

外形

Sterile filtered and lyophilized from 10 mM Sodium Phosphate, pH 7.5.

储存及稳定性

The lyophilized protein is stable for a few weeks for at room temperature but is best stored at -20ºC. Reconstitute in 10 mM Sodium Phosphate, pH7.5 to a concentration of 0.1-1 mg/mL. This solution can be diluted into other aqueous buffers and stored at 2-8ºC for one week or -20ºC for future use. Reconstituted sCD40L/TRAP should be stored at -20ºC in undiluted aliquots for up to 6 months. Freeze/thaw cycles will result in significant loss of activity.

分析说明

Specific Activity: GF101 is fully biologically active as determined by the dose-dependent stimulation of IL-8 production by human PBMC.The expected ED50 for this effect is 5-10 ng/ml.Note: Results may vary with PBMC donors.

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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