产品说明
一般描述
PR domain proteins (PRDMs) have been associated with many types of human cancers. PRDM14 was found to be up-regulated in breast cancer cells. The expression of PRDM14 to breast cancer cells actually increased cell proliferation and decreased the effect of chemotherapeutic drugs, while down-regulation of PRDM14 did the opposite. In addition to breast cancer, PRDM14 has recently been linked to non-small cell lung cancer development. PRDM14 also seems to play a role in the preservation of the self-renewal of human embryonic stem cells and transcriptional regulation.
特异性
This antibody recognizes the N-terminus of PRDM14.
免疫原
GST-tagged recombinant protein corresponding to the N-terminus of human PRDM14.
应用
This Anti-PRDM14 Antibody is validated for use in WB for the detection of PRDM14.
质量
Evaluated by Western Blot in human lung tissue lysate.
Western Blot Analysis: A 1:1000 dilution of this antibody detected PRDM14 in 10 µg of human lung tissue lysate.
目标描述
~62 kDa observed
外形
Affinity purified
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 纯化方式 | affinity chromatography |
| species reactivity | rat, mouse, human |
| technique(s) | western blot: suitable |
| NCBI登记号 | NP_078780 |
| UniProt登记号 | Q9GZV8 |
| 运输 | wet ice |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
