产品说明
免疫原
Peptide sequence around aa. 421-425/400-404/419-423 (R-S-T-M-V), according to the proteins PAK1/PAK2/PAK3.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
目标描述
The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2.
外形
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
基本信息
| MDL编号 | MFCD02097133 |
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 61-67 kDa 68-74 kDa |
| species reactivity | mouse, human, rat |
| 浓度 | 1 mg/mL |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 indirect immunofluorescence: 1:100-1:200 |
| 同位素/亚型 | IgG |
| 免疫原序列 | (R-S-T-M-V) |
| NCBI登记号 | NP_001121638.1 NP_001122092.1 NP_002568.2 |
| UniProt登记号 | Q13177 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... PAK1(5058), PAK2(5062), PAK3(5063) |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
