产品说明
免疫原
Peptide sequence around aa. 180-184 (T-G-Y-V-A), according to the protein MAPK14.
特点和优势
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目标描述
Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. May play a role in stabilization of EPO mRNA during hypoxic stress. Isoform Mxi2 activation is stimulated by mitogens and oxidative stress and only poorly phosphorylates ELK1 and ATF2. Isoform Exip may play a role in the early onset of apoptosis.
外形
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
基本信息
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
偶联物 | unconjugated |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
分子量 | ~43 kDa |
species reactivity | mouse, human, rat |
浓度 | 1 mg/mL |
technique(s) | western blot: 1:500-1:1000 |
同位素/亚型 | IgG |
免疫原序列 | (T-G-Y-V-A) |
NCBI登记号 | NP_001306.1 |
UniProt登记号 | Q16539 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... MAPK14(1432) |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |