Anti-Collagen Type I Antibody

产品说明

一般描述

Collagens are highly conserved throughout evolution and are characterised by an uninterrupted "Glycine X Y" triplet repeat that is a necessary part of the triple helical structure. Type I collagen (95 kDa) is found in bone, cornea, skin and tendon. Mutations in the encoding gene are associated with osteogenesis imperfecta, Ehlers Danlos syndrome, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for Platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor.

免疫原

Rat tail collagen

应用

Research Category
Cell Structure
Specificity ELISA Analysis: A representative lot detected mouse and rat collagen but not human collagen in ELISA.

Western Blot Analysis: A 1:2,000 dilution from a representative lot detected Collagen Type 1 on 10 µg of rat skin tissue lysate.
Research Sub Category
Adhesion (CAMs)
Detect Collagen Type I using this Anti-Collagen Type I Antibody validated for use in Western Blotting, IHC(P), ELISA.

质量

Evaluated by Immunohistochemistry in rat skin tissue.

Immunohistochemistry Analysis: A 1:100 dilution of this antibody detected Collagen Type 1 in rat skin tissue.

目标描述

130 kDa calculated

联系

Replaces: AB755P

外形

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Affinity purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
Rat skin tissue

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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