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Anti-CASP1 (p20, Cleaved-Asn120) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4503273
规格纯度
affinity isolated antibody
参考价格
4618.16 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Caspase-1 is also known as interleukin-1β converting enzyme (ICE). It is located on human chromosome 11q22.2. It has 10 exons, an N terminal CARD (caspase activation and recruitment domain), a large P20 subunit and a small P10 subunit. CASP1 is present in leukocytes, monocytes and epithelial cells.
Anti-CSPN1 (p20, Cleaved-Asn120) Antibody detects endogenous levels of fragment of activated CSPN1 (p20, Cleaved-Asn120) protein.

免疫原

The antiserum was produced against synthesized peptide derived from human Caspase 1.

Immunogen Range: 101-150

生化/生理作用

Caspase-1 can transform pro-inflammatory cytokines, interleukin-1β (IL-1β) and IL-18 into their active forms. It participates in pyroptosis. It is overexpressed in the aorta of coronary atherosclerosis patients. CASP1 helps in host cell survival by inducing membrane biogenesis to restore the impairment caused by pore-forming toxins.

特点和优势

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外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量antigen 18 kDa
species reactivityhuman
浓度~1 mg/mL
technique(s)ELISA: 1:20000
western blot: 1:500-1:1000
NCBI登记号P29466
UniProt登记号P29466
运输wet ice
储存温度−20℃
Gene Informationhuman ... CASP1(834)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable

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