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IL-4 human

品牌
Sigma-Aldrich
货号
SRP6172
规格纯度
recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)
参考价格
5531.78 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Interleukin-4 (IL-4) is a pleiotropic cytokine and a potent lymphoid cell growth factor. It is produced by activated T cells and is a ligand for interleukin 4 receptor. The gene encoding this protein is localized on human chromosome 5q31.1. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

生化/生理作用

Interleukin-4 (IL-4) stimulates the growth and survivability of certain B cells and T cells. The interleukin 4 receptor also binds to interleukin-13 (IL-13), which may contribute to many overlapping functions of this cytokine and IL-13. STAT6 (signal transducer and activator of transcription-6) has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This protein exhibits anti-inflammatory responses and has a role in immune processes by protecting against intracellular pathogens.

外形

Lyophilized from a solution of 20 mM Tris-HCl, pH 7.4, with 300 mM NaCl.

制备说明

Centrifuge the vial prior to opening.

重悬

Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.

基本信息

NACRESNA.32

产品性质

生物来源human
重组expressed in HEK 293 cells
测定≥95% (SDS-PAGE)
形式lyophilized
分子量 (14 and 19 kDa, monomer)
包装pkg of 10 μg
technique(s)cell culture | mammalian: suitable
NCBI登记号P05112
运输dry ice
储存温度−70℃
Gene Informationhuman ... IL4(3565)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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