产品说明
包装
25, 50 mL in glass bottle
应用
Technical Article Comparing Performance of Different Enzymes
Learn more
about recent application data generated by Sigma R&D to optimize hydrolysis for different drug classes using enzymes from different sources and the use of a chromatographicaly purified enzyme to reduce the effect of esterase activity resulting in conversion of 6-MAM to Morphine.
生化/生理作用
β-Glucuronidase (GUSB) is a lysosomal enzyme, that degrades glucuronate-containing glycosaminoglycans. β-glucuronidase, obtained from abalone has the ability to hydrolyze samples, that has high analyte concentrations. Absence of β-glucuronidase results in mucopolysaccharidosis type VII (MPSVII), which leads to lysosomal storage in the brain.
单位定义
One Sigma or modified Fishman unit will liberate 1.0 μg of phenolphthalein from phenolphthalein glucuronide per hr at 37 ℃ at pH 3.8 (30 min assay).
外形
Supplied as an aqueous solution containing
基本信息
| 酶学委员会(EC)编号 | 3.1.2.31 ( BRENDA | IUBMB ) |
| MDL编号 | MFCD00130629 |
| NACRES | NA.54 |
产品性质
| 质量水平 | 200 |
| 形式 | aqueous solution |
| β-glucuronidase activity | ≥20,000,000 units/g protein 150,000-250,000 units/mL |
| secondary activity | ≤7,500 units/mL sulfatase |
| 储存温度 | 2-8℃ |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
