产品介绍：
产品说明
应用
R-(+)-DIOA has been used as a potassium/chloride K+-Cl- transport inhibitor to study its effects on:
- short circuit current (Isc) in rat semicircular canal duct (SCCD) epithelium
- uptake of grepafloxacin by THP-1 monocytes
- the uptake of moxifloxacin by THP-1 monocytes
包装
10, 50 mg in glass bottle
生化/生理作用
[(dihydroindenyl)oxy]acetic acid (DIOA) acts as a potent inhibitor of potassium/chloride (K+–Cl−) co-transporter. It does not exert its effects on bumetanimide-sensitive [Na+,K+,Cl-]-cotransport system.
基本信息
| 经验(实验)分子式 | C20H24Cl2O4 |
| 分子量 | 399.31 |
| MDL编号 | MFCD00069261 |
| PubChem化学物质编号 | 24277830 |
产品性质
| 测定 | ≥98% (HPLC) |
| 形式 | solid |
| 旋光性 | [α]27/D +18.1°, c = 0.7 in methanol(lit.) |
| 颜色 | white |
| 溶解性 | H2O: insoluble <0.11 mg/mL DMSO: >20 mg/mL 0.1 M HCl: insoluble 0.1 M NaOH: soluble ethanol: soluble |
| SMILES string | CCCC[C@]1(Cc2cc(OCC(O)=O)c(Cl)c(Cl)c2C1=O)C3CCCC3 |
| InChI | 1S/C20H24Cl2O4/c1-2-3-8-20(13-6-4-5-7-13)10-12-9-14(26-11-15(23)24)17(21)18(22)16(12)19(20)25/h9,13H,2-8,10-11H2,1H3,(H,23,24)/t20-/m0/s1 |
| InChI key | YAWWQIFONIPBKT-FQEVSTJZSA-N |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
