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Zotepine

佐替平

品牌
Sigma-Aldrich
CAS
26615-21-4
货号
Z0877
包装型号
规格纯度
参考价格
1027.89 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

应用

Zotepine has been used as an anti-psychotic agent:

  • in biophysical studies with serotonin 2A receptor (5-HT2AR)
  • to study its effects on the inhibition of human organic cation transporter 1 (hOCT1)
  • to study its protective effects on the human embryonic kidney (HEK cells)

包装

10, 50 mg in glass bottle

生化/生理作用

Zotepine acts as an antagonist of dopamine D1, D2, and serotonin (5-HT2A/2C) receptors, and noradrenaline transporters. It shows therapeutic effects against schizophrenia and acute mania.
Zotepine is an atypical antipsychotic.

特点和优势

This compound was developed by Astellas. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

其他说明

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. Z0877.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

基本信息

经验(实验)分子式C18H18ClNOS
分子量331.86
MDL编号MFCD00868143
PubChem化学物质编号329831602
NACRESNA.77

产品性质

测定>98% (HPLC)
质量水平100
形式powder
颜色 white to off-white
溶解性DMSO: ≥20 mg/mL
创始人Astellas
储存温度room temp
SMILES stringCN(C)CCOC1=Cc2ccccc2Sc3ccc(Cl)cc13
InChI1S/C18H18ClNOS/c1-20(2)9-10-21-16-11-13-5-3-4-6-17(13)22-18-8-7-14(19)12-15(16)18/h3-8,11-12H,9-10H2,1-2H3
InChI keyHDOZVRUNCMBHFH-UHFFFAOYSA-N

安全信息

象形图GHS07GHS09
警示用语:Warning
危险声明H302 - H400
预防措施声明P273
危险分类Acute Tox. 4 Oral - Aquatic Acute 1
储存分类代码6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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