位置:首页 > 品牌 > Sigma-Aldrich >

Imatinib mesilate

甲磺酸伊马替尼

CAS
220127-57-1
货号
Y0001691
规格纯度
European Pharmacopoeia (EP) Reference Standard
参考价格
1572.27 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

甲磺酸伊马替尼是一种具有抗肿瘤活性的酪氨酸激酶抑制剂。伊马替尼能够抑制由bcr-abl致癌基因编码的Bcr-Abl激酶以及由c-kit和血小板源性生长因子受体(PDGFR)致癌基因编码的受体酪氨酸激酶。甲磺酸伊马替尼通过抑制由CML中费城染色体异常产生的Bcr-Abl酪氨酸激酶,降低了白血病CML和ALL的增殖并诱导其凋亡。 在过度表达c-kit的疾病中,如胃肠道间质瘤(GIST),通过抑制c-kit酪氨酸活性,可抑制肥大细胞和细胞增殖。

包装

Unit quantity: 120 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C29H31N7O · CH4O3S
分子量589.71
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
InChI1S/C29H31N7O.CH4O3S/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36;1-5(2,3)4/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34);1H3,(H,2,3,4)
InChI keyYLMAHDNUQAMNNX-UHFFFAOYSA-N

安全信息

象形图GHS08
警示用语:Warning
危险声明H361d
预防措施声明P201 - P202 - P280 - P308 + P313 - P405 - P501
危险分类Repr. 2
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

推荐产品
| 首页 | 联系我们 | 会员服务 | 广告服务 | 友情链接 |
版权所有 CopyRight © 2008-2024 粤ICP备08119708号