产品说明
一般描述
Serum response factor (SRF) is a nuclear transcription factor that binds to the serum response element (SRE), and is essential for embryonic development of the mesoderm, as well as for the maintenance of adult muscle cells and neurons. As this protein is involved in the downstream regulation of many immediate-early genes, it participates in a variety of cell functions, including cell cycle, apoptosis, cell growth, and cell differentiation. SRF is most commonly activated by serum, LPA, LPS, TPA, growth factors, including TNFalpha, as well as antioxidants and UV light.
特异性
A weak interaction with mouse has also been observed. Reactivity with other species has not been tested.
This monoclonal antibody recognizes SRF.
免疫原
Synthetic human SRF peptide, a.a. 406-508.
应用
Detect SRF [Serum Response Factor] using this Anti-SRF [Serum Response Factor] Antibody, clone 1E1 validated for use in WB & IC.
Research Sub Category
Mesenchymal Stem Cells
Neural Stem Cells
Research Category
Stem Cell Research
Immunocytochemistry: Recommended working dilution is 1:500.
质量
(Based upon representative data from a previous lot).
Western Blotting: Recommended working dilution is 0.5 µg/mL.
目标描述
~52 kDa
外形
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl, and 0.05% sodium azide.
Format: Purified
Protein G Purified
储存及稳定性
Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months. Avoid repeat freeze/thaw cycles.
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
产品性质
| 生物来源 | mouse |
| 抗体形式 | purified antibody |
| antibody product type | primary antibodies |
| 克隆 | 1E1, monoclonal |
| species reactivity | mouse, human |
| technique(s) | immunocytochemistry: suitable western blot: suitable |
| input | sample type mesenchymal stem cell(s) sample type neural stem cell(s) |
| 同位素/亚型 | IgG1κ |
| UniProt登记号 | P11831 |
| 运输 | wet ice |
| Gene Information | human ... ELK3(2004) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
