产品介绍：
产品说明
一般描述
Sphingosine is the most bioactive sphingoid with the common long chain base in sphingolipids. It is a constituent of the cell membrane. 7-nitro-2-1,3-benzoxadiazol-4-yl (NBD) sphingosine is a derivative of sphingosine attached with the fluorescent probe, NBD group.
应用
NBD Sphingosine or omega(7-nitro-2-1,3-benzoxadiazol-4-yl)(2S,3R,4E)-2-aminooctadec-4-ene-1,3-diol may be used:
- as a negative control to determine the binding of Atg12-Atg5 conjugate with phosphatidylethanolamine (PE)-containing liposomes
- to label sphingosine kinase 1 (SphK1) in order to determine its role in endocytic membrane trafficking
- to generate 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD)-ceramide C16
生化/生理作用
Sphingosine serves as a precursor for ceramide. It is involved in the inhibition of protein kinase C in human platelets.
包装
5 mL Amber Glass Screw Cap Vial (810205X-250ug)
基本信息
| 经验(实验)分子式 | C24H39N5O5 |
| 分子量 | 477.60 |
| NACRES | NA.25 |
产品性质
| 测定 | >99% (TLC) |
| 包装 | pkg of 1 × 1 mL (810205X-250ug) |
| manufacturer/tradename | Avanti Polar Lipids 810205X |
| 浓度 | 0.25 mg/mL (810205X-250ug) |
| 运输 | dry ice |
| 储存温度 | −20℃ |
安全信息
| 象形图 |   |
| 警示用语： | Danger |
| 危险声明 | H302 + H312 - H315 - H319 - H331 - H336 - H351 - H361d - H370 - H372 |
| 预防措施声明 | P260 - P280 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P311 - P403 + P233 |
| 危险分类 | Acute Tox. 3 Inhalation - Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 1 - STOT SE 3 |
| 靶器官 | Central nervous system |
| 储存分类代码 | 3 - Flammable liquids |
| WGK | WGK 3 |
| 闪点(F) | 125.5 °F |
| 闪点(C) | > 51.95 ℃ |
