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Monoclonal Anti-WDR62 antibody produced in mouse

品牌
Sigma-Aldrich
货号
W3269
规格纯度
~1.0 mg/mL, clone 3G8, purified immunoglobulin, buffered aqueous solution
参考价格
7167.64 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Monoclonal Anti-WDR62 (mouse IgG2a isotype) is derived from the hybridoma 3G8 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a fusion protein encoding a fragment of human WDR62. WD repeat 62 is a member of WD-repeats and contains 15 WD repeats. WD-repeats consists of minimally conserved domains of 40-60 amino acids, which are initiated by glycine-histidine (GH) dipeptide 11 to 24 residues from the N-terminus and ends with tryptophan-aspartic acid (WD) dipeptide at the C terminus.

应用

Monoclonal Anti-WDR62 antibody produced in mouse has been used in immunoblotting and immunofluorescence.

生化/生理作用

WD repeat 62 (WDR62) is identified in a phosphoproteome analysis as a protein associated with the mitotic spindle. It physically interacts with RNA-binding protein (RALY), TATA-binding protein (TBP), C1 or f103, mitogen-activated protein kinase (MAPK9) and itself. WDR62 potentiates c-Jun N-terminal kinase (JNK) activity. Mutations in this gene are linked to microcephaly and cortical malformations.

目标描述

WDR62 contains 15 WD repeats and has been identified in aphosphoproteome analysis as a protein associated with the mitotic spindle. WD40 proteins are implicated in many essential biologicalfunctions including adaptor/regulatory modules in signaltran

外形

0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

产品性质

质量水平200
生物来源mouse
偶联物unconjugated
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆3G8, monoclonal
形式buffered aqueous solution
分子量antigen ~170 kDa
species reactivityhuman
浓度~1.0 mg/mL
technique(s)indirect immunofluorescence: 0.5-1 μg/mL using HEK-293T cells over expressing human WDR62
western blot: 0.5-1 μg/mL using HEK-293T cells over expressing human WDR62
同位素/亚型IgG2a
UniProt登记号O43379
运输dry ice
储存温度−20℃
Gene Informationhuman ... WDR62(284403)

Sigma-Aldrich

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