产品说明
一般描述
Translocase of outer mitochondrial membrane 22 (TOMM22) is an essential receptor of the mitochondrial import channel. It is characterized with an N-terminal negatively charged region exposed to the cytosol, a putative transmembrane region and a C-terminal intermembrane space region with little negative charge.
免疫原
membrane fraction from Vero (monkey kidney-derived) cells.
应用
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)
- Western blotting
生化/生理作用
Translocase of outer mitochondrial membrane 22 (TOMM22) is a key constituent of TOM complex. It functions as a mitochondrial receptor for the proapoptotic protein Bax (BCL2-associated X protein). TOMM22 interacts with 3-β hydroxysteroid dehydrogenase 2 (3βHSD2) and converts pregnenolone-to-progesterone in steroidogenic cells.
外形
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% BSA and 15 mM sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| MDL编号 | MFCD03457578 |
| NACRES | NA.41 |
产品性质
| 质量水平 | 200 |
| 生物来源 | mouse |
| 偶联物 | unconjugated |
| 抗体形式 | purified from hybridoma cell culture |
| antibody product type | primary antibodies |
| 克隆 | 1C9-2, monoclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen 22 kDa |
| species reactivity | human, monkey |
| should not react with | rodent |
| 浓度 | ~1 mg/mL |
| technique(s) | immunocytochemistry: suitable microarray: suitable western blot: 0.5-1.0 μg/mL using whole extract of cultured human lymphoma Raji cells. |
| 同位素/亚型 | IgG1 |
| UniProt登记号 | Q9NS69 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... TOMM22(56993) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
