产品介绍：
产品说明
应用
Tyrphostin 51 has been used to study the inhibition of rat hepatic leptin 1.
包装
5 mg in glass bottle
25 mg in poly bottle
生化/生理作用
Tyrphostin 51 is a small molecule inhibitor of epidermal growth factor (EGF) receptor kinase function. This molecule associates with the substrate subsite of the protein tyrosine kinase (PTK) domain,.
EGFR tyrosine kinase inhibitor.
特点和优势
This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
制备说明
5 mg of Tyrphostin 51 is soluble in 0.1 ml of DMSO and yields a clear, orange to red solution.
基本信息
| 经验(实验)分子式 | C13H8N4O3 |
| 分子量 | 268.23 |
| MDL编号 | MFCD00133903 |
| PubChem化学物质编号 | 24278756 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 200 |
| 生物来源 | synthetic (organic) |
| 测定 | ≥98% |
| 形式 | powder |
| 效能 | 0.8 μM IC50 |
| 溶解性 | DMSO: soluble 5 mg of Tyrphostin 51 in 0.1 ml of solvent, clear, orange to red |
| 储存温度 | 2-8℃ |
| SMILES string | NC(\C(=C\c1cc(O)c(O)c(O)c1)C#N)=C(/C#N)C#N |
| InChI | 1S/C13H8N4O3/c14-4-8(12(17)9(5-15)6-16)1-7-2-10(18)13(20)11(19)3-7/h1-3,18-20H,17H2/b8-1+ |
| InChI key | JKNOYWVMHPMBEL-UNXLUWIOSA-N |
| Gene Information | human ... CDK2(1017), EGFR(1956) |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
