产品说明
一般描述
Syntaxin 7 is a 35kDa protein and is a member of t-Soluble N-ethylmaleimide-sensitive factor activating protein receptor (SNARE) protein family. It is widely expressed in multiple tissues.
免疫原
synthetic peptide corresponding to amino acids 131-149 located at the mid-region of rat syntaxin 7, conjugated to KLH. This sequence is highly conserved (two amino acid substitutions) in mouse and human syntaxin 7 (~80% identity).
应用
Anti-Syntaxin 7 antibody produced in rabbit has been used in immunoblotting and immunofluorescence.
生化/生理作用
Syntaxin 7, localized on membrane compartments of late endosomes, facilitates fusion of late endosomes with lysosomes. The protein also helps in lysosomal biogenesis. Mutant syntaxin 7 lacking the transmembrane domain blocks endocytic transport from the early to late endosome. Syntaxin 7 has been described to play an important role during phagocytosis.
外形
0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| MDL编号 | MFCD06798547 |
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 200 |
| 偶联物 | unconjugated |
| 抗体形式 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen 35 kDa |
| species reactivity | rat |
| technique(s) | indirect immunofluorescence: 1:500-1:1000 using of rat kidney NRK cell line western blot: 1:1000-1:2000 using whole cell extract of rat kidney NRK cell line |
| UniProt登记号 | O70257 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | rat ... Stx7(60466) |
