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Monoclonal Anti-Sonic Hedgehog (N-terminal) antibody produced in rat

品牌
Sigma-Aldrich
货号
S4944
规格纯度
clone 171018, purified immunoglobulin, lyophilized powder
参考价格
4731.57 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

免疫原

purified, E. coli-derived, recombinant mouse sonic hedgehog N-terminal peptide (amino acids 25-198).

生化/生理作用

Shh protein is secreted by Purkinje cells in the cerebellum with both autocrine and paracrine functions. The Shh signaling is mediated by the interaction of Shh with transmembrane proteins, Patched and Smoothened. The Shh pathway cross-talks Notch and Wnt pathways and acts via downstream targets such as cyclins, gamma catenin, myc and other transcription factors. The Hh family members have multiple roles as morphogens, cell survival factors, setting anterior-posterior axis and digit formation during development of limb and axon guidance factors during the development of brain and nervous system.

外形

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD06798717
NACRESNA.41

产品性质

质量水平100
生物来源rat
偶联物unconjugated
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆171018, monoclonal
形式lyophilized powder
species reactivitymouse, human
technique(s)capture ELISA: suitable
immunohistochemistry (frozen sections): 25 μg/mL using mouse embryo
neutralization: suitable
western blot: 1-2 μg/test
同位素/亚型IgG2a
UniProt登记号Q15465
储存温度−20℃
Gene Informationhuman ... SHH(6469)
mouse ... Shh(20423)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)

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