产品说明
一般描述
Somatostatin receptor 2 (SSTR2) is encoded by the gene mapped to human chromosome 17q25.1. It is mainly localized on choroid plexus and arachnoid granulations. SSTR2 is transcribed into two isoforms, SSTR2A and SSTR2B through alternative splicing.
免疫原
synthetic peptide corresponding to the second extracellular loop of human somatostatin receptor type 2, conjugated to KLH. The immunizing peptide has 100% homology with the rat and mouse gene.
生化/生理作用
Somatostatin receptor 2 (SSTR2) mediates human anterior pituitary hormone suppression by interacting with its peptide ligand somatostatin. It also plays a major role in maintenance of brain fluid homeostasis. The encoded protein has an ability to hinder the cell proliferation of solid tumors. Experimental studies states that SSTR2 methylation is presumed to be involved in the metastasis and invasion of laryngeal cancer.
外形
Solution in phosphate buffered saline, pH 7.7, containing 0.1% sodium azide.
基本信息
| MDL编号 | MFCD02097419 |
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 200 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| species reactivity | human |
| availability | not available in Japan |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 24 μg/mL using human pancreas, Islets of Langerhans (Optimal dilution should be determined by the researcher.) |
| UniProt登记号 | P30874 |
| 运输 | dry ice |
| 储存温度 | −70℃ |
| Gene Information | human ... SSTR2(6752) mouse ... Sstr2(20606) rat ... Sstr2(54305) |
